Institute of Ophthalmology-Clínica Girona (IOC) 
Juli Garreta, 13 2on pis · 17002 Girona
CIF B17356932
  Girona Mercantile Register
Volume 1198
Book 0
Page 57
Sheet 8
Folder GI-10123
Entry 5


Limbic Deficiency Syndrome

Definition: Stem cells on the periphery of the cornea affectation, which are responsible for the regeneration of the epithelium (most superficial layer of the cornea). This destruction of epithelial stem cells can be congenital (birth) or acquired (by a burn, a conjunctival scarring ...)

  1. In mild cases, treatment is medical (tears and anti-inflammatory eye drops) (51) but in severe cases, it is necessary to resort to partial or total limbal transplantation.
Limbic Deficiency Syndrome